2-乙基-7-硝基-1,2,3,4-四氢异喹啉合成路线 （共 3 条）
反应条件
sodium tris(acetoxy)borohydride in acetic acid; 1,2-dichloro-ethane
T=25°C; Reduction; alkylation; 72 h;
参考文献
Chan, Wai N.; Hadley, Michael S.; Harling, John D.; Herdon, Hugh J.; Orlek, Barry S.; Riley, Graham J.; Stead, Rachel E. A.; Stean, Tania O.; Thompson, Mervyn; Upton, Neil; Ward, Robert W.
Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 8 p. 2085 - 2094
反应条件
1: 86 percent / conc. H2SO4 / acetic acid / 20 h / 25 °C
2: 11 g / K2CO3 / methanol; H2O / 18 h
3: sodium triacetoxyborohydride / 1,2-dichloro-ethane; acetic acid / 72 h / 25 °C
View Scheme
参考文献
Chan, Wai N.; Hadley, Michael S.; Harling, John D.; Herdon, Hugh J.; Orlek, Barry S.; Riley, Graham J.; Stead, Rachel E. A.; Stean, Tania O.; Thompson, Mervyn; Upton, Neil; Ward, Robert W.
Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 8 p. 2085 - 2094
反应条件
1: 11 g / K2CO3 / methanol; H2O / 18 h
2: sodium triacetoxyborohydride / 1,2-dichloro-ethane; acetic acid / 72 h / 25 °C
View Scheme
参考文献
Chan, Wai N.; Hadley, Michael S.; Harling, John D.; Herdon, Hugh J.; Orlek, Barry S.; Riley, Graham J.; Stead, Rachel E. A.; Stean, Tania O.; Thompson, Mervyn; Upton, Neil; Ward, Robert W.
Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 8 p. 2085 - 2094
