反应条件
1.1: methanol; ammonia / 16 h / 0 - 60 °C 2.1: 1H-imidazole; 4-(N,N-dimethlyamino)pyridine / N,N-dimethyl-formamide / 0.5 h 3.1: trifluoroacetic acid / water; tetrahydrofuran / 0 °C 4.1: (tetrazol-5-yl)benzene / dichloromethane / 1 h 4.2: 0.5 h / 0 °C 5.1: trifluoroacetic acid / water / 20 h / 0 °C View Scheme
参考文献
Moreau, Christelle; Kirchberger, Tanja; Swarbrick, Joanna M.; Bartlett, Stephen J.; Fliegert, Ralf; Yorgan, Timur; Bauche, Andreas; Harneit, Angelika; Guse, Andreas H.; Potter, Barry V. L.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 24 p. 10079 - 10102
