5-甲氧基吲哚-3-乙醇合成路线 （共 19 条）
反应条件
sulfuric acid in N,N-dimethyl acetamide T=55°C; Fischer Indole Synthesis; 2 h;
参考文献
Tetrahedron Letters, , vol. 54, # 40 p. 5489 - 5491
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran T=0 - 65°C; 0.333333 h; 2: With water in tetrahydrofuran; ethyl acetate
参考文献
WO2012/110986 A1, ;
Page/Page column 51 ;
WO 2012/110986 A1
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran T=20°C; 0.166667 h;
参考文献
Synthesis, , # 2 p. 267 - 275
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=20°C;
参考文献
Journal of Medicinal Chemistry, , vol. 50, # 25 p. 6436 - 6440
反应条件
lithium borohydride in methanol; diethyl ether T=20°C;
参考文献
Bioorganic and Medicinal Chemistry, , vol. 13, # 24 p. 6810 - 6822
反应条件
L-(+)-tartaric acid-urea melt T=70°C; Fischer Indole Synthesis;
参考文献
Organic Letters, , vol. 14, # 17 p. 4568 - 4571
反应条件
lithium aluminium tetrahydride in diethyl ether 0.5 h; Heating;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 7 p. 813 - 822
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=20°C; 4 h;
参考文献
Chemical Communications, , vol. 50, # 10 p. 1231 - 1233
反应条件
1.1: BuLi / tetrahydrofuran; hexane / 0.25 h / -10 °C 1.2: tetrahydrofuran; hexane / 3 h / 0 °C 2.1: 5.4 g / NBS / tetrahydrofuran; hexane / 3 h / -78 °C 3.1: t-BuLi / pentane; tetrahydrofuran / 0.17 h / -78 °C 3.2: 56 percent / pentane; tetrahydrofuran / 0.25 h / -78 °C 4.1: 84 percent / Bu4NF / tetrahydrofuran / 0.17 h / 20 °C View Scheme
参考文献
Synthesis, , # 2 p. 267 - 275
反应条件
1.1: 5.4 g / NBS / tetrahydrofuran; hexane / 3 h / -78 °C 2.1: t-BuLi / pentane; tetrahydrofuran / 0.17 h / -78 °C 2.2: 56 percent / pentane; tetrahydrofuran / 0.25 h / -78 °C 3.1: 84 percent / Bu4NF / tetrahydrofuran / 0.17 h / 20 °C View Scheme
参考文献
Synthesis, , # 2 p. 267 - 275
