2-溴-2-(4-氟苯基)乙酸乙酯合成路线 （共 4 条）
反应条件
N-bromosuccinmide; hydrogen bromide in tetrachloromethane 3 h; Heating / reflux;
参考文献
Heiman, Mark Louis; Sindelar, Dana Kevin
Patent: US2005/277677 A1, 2005 ;
Location in patent: Page/Page column 6 ;
US 20050277677 A1
反应条件
phosphorus tribromide in chloroform T=0 - 20°C; 7 h; Inert atmosphere;
参考文献
Poon, Jia-Fei; Alao, John Patrick; Sunnerhagen, Per; Diner, Peter
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 27 p. 4526 - 4536
反应条件
1.1: dichloromethane / 0.17 h / 0 °C / |Inert atmosphere 1.2: 4.25 h / |Inert atmosphere 2.1: sodium tetrahydroborate / ethanol / 1 h / -30 °C / |Inert atmosphere 3.1: phosphorus tribromide / chloroform / 7 h / 0 - 20 °C / |Inert atmosphere View Scheme
参考文献
Organic and Biomolecular Chemistry, , vol. 11, # 27 p. 4526 - 4536
反应条件
1: sodium tetrahydroborate / ethanol / 1 h / -30 °C / |Inert atmosphere 2: phosphorus tribromide / chloroform / 7 h / 0 - 20 °C / |Inert atmosphere View Scheme
参考文献
Organic and Biomolecular Chemistry, , vol. 11, # 27 p. 4526 - 4536
