5-甲酰基-1H-吡咯-2-羧酸合成路线 (共 3 条)
反应条件
sodium hydroxide in methanol
参考文献
Jones, Matthew A.; Morton, James D.; Coxon, James M.; McNabb, Stephen B.; Lee, Hannah Y.-Y.; Aitken, Steven G.; Mehrtens, Janna M.; Robertson, Lucinda J.G.; Neffe, Axel T.; Miyamoto, Shigeru; Bickerstaffe, Roy; Gately, Karl; Wood, Jacqueline M.; Abell, Andrew D.
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 14 p. 6911 - 6923
反应条件
lithium hydroxide in methanol; water 2 h; Heating;
参考文献
Schmuck, Carsten; Graupner, Svea
Tetrahedron Letters, 2005 , vol. 46, # 8 p. 1295 - 1298
反应条件
1: 61 percent / POCl3 / 1,2-dichloro-ethane / 0.25 h / Heating 2: 60 percent / aq. KOH / 2 h / 40 - 50 °C View Scheme
参考文献
Organic and Biomolecular Chemistry, , vol. 1, # 12 p. 2103 - 2110