4-甲酰基-1H-吡咯-2-羧酸合成路线 (共 4 条)
反应条件
sodium hydroxide in tetrahydrofuran
参考文献
Jones, Matthew A.; Morton, James D.; Coxon, James M.; McNabb, Stephen B.; Lee, Hannah Y.-Y.; Aitken, Steven G.; Mehrtens, Janna M.; Robertson, Lucinda J.G.; Neffe, Axel T.; Miyamoto, Shigeru; Bickerstaffe, Roy; Gately, Karl; Wood, Jacqueline M.; Abell, Andrew D.
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 14 p. 6911 - 6923
反应条件
potassium hydroxide; water 1) 0 deg C; 2) room temperature, 1.5 h;
参考文献
Anderson, Hugh J.; Clase, J. Andrew; Loader, Charles E.
Synthetic Communications, 1987 , vol. 17, # 4 p. 401 - 408
反应条件
1: 75 percent / AlCl3 / CH2Cl2; nitromethane / 18 h / -20 °C 2: 86 percent / 20percent aq. NaOH / 1 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 53, # 2 p. 403 - 407
反应条件
copper (II) chromite in quinoline T=185°C; 0.2 h;
参考文献
Anderson, Hugh J.; Clase, J. Andrew; Loader, Charles E.
Synthetic Communications, 1987 , vol. 17, # 4 p. 401 - 408