2-甲基-1-(1-哌嗪基)-1-丙酮合成路线 （共 3 条）
反应条件
hydrogenchloride in methanol
T=0 - 20°C;
参考文献
BIOMARIN PHARMACEUTICAL INC.; WANG, Bing; CHU, Daniel
Patent: WO2011/130661 A1, 2011 ;
Location in patent: Page/Page column 98; 106 ;
反应条件
20 PdO/C in ethanol; cyclohexane
T=80°C; 3 h;
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2004/41829 A1, 2004 ;
Location in patent: Page 74 ;
WO 2004/041829 A1
反应条件
sodium hydroxide; triethylamine; trifluoroacetic acid in methanol; dichloromethane
参考文献
Shiseido Co., Ltd.
Patent: US5756505 A1, 1998 ;
