2,4,6-三甲基-5-羟基嘧啶(6ci,9ci)合成路线 （共 4 条）
反应条件
1: in water
T=80°C; 6 h;
2: With sodium hydroxide in water
T=80°C; 8 h;
参考文献
Renard, Brice-Loic; Boucherle, Benjamin; Maurin, Bruno; Molina, Marie-Carmen; Norez, Caroline; Becq, Frederic; Decout, Jean-Luc
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 5 p. 1935 - 1941
反应条件
ammonium hydroxide
T=180°C; 10 h;
参考文献
Valgimigli, Luca; Brigati, Giovanni; Pedulli, Gian Franco; DiLabio, Gino A.; Mastragostino, Marina; Arbizzani, Catia; Pratt, Derek A.
Chemistry - A European Journal, 2003 , vol. 9, # 20 p. 4997 - 5010
反应条件
para-nitroperbenzoic acid in acetone
T=25 - 40°C;
参考文献
Gashev, S. B.; Lezina, V. P.; Smirnov, L. D.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1983 , vol. 19, # 9 p. 1003 - 1007
Khimiya Geterotsiklicheskikh Soedinenii, 1983 , # 9 p. 1252 - 1256
反应条件
1: 94 percent / p-nitroperbenzoic acid / acetone / 25 - 40 °C
2: 33 percent / H2O / 3 h / 100 °C
View Scheme
参考文献
Gashev, S. B.; Lezina, V. P.; Smirnov, L. D.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1983 , vol. 19, # 9 p. 1003 - 1007
Khimiya Geterotsiklicheskikh Soedinenii, 1983 , # 9 p. 1252 - 1256
