1: 97 percent / methanol; tetrahydrofuran / 1.) 0 deg C, 0.5 h, 2.) room temperature, 12 h 2: 76 percent / 10 percent aq. HCl / 0.5 h / Ambient temperature View Scheme

1: 97 percent / methanol; tetrahydrofuran / 1.) 0 deg C, 0.5 h, 2.) room temperature, 12 h 2: 76 percent / 10 percent aq. HCl / 0.5 h / Ambient temperature 3: 97 percent / 10 percent aq. HCl / dioxane / 1 h / Heating 4: SOCl2 / 5 h / Heating View Scheme

1: 97 percent / methanol; tetrahydrofuran / 1.) 0 deg C, 0.5 h, 2.) room temperature, 12 h 2: 76 percent / 10 percent aq. HCl / 0.5 h / Ambient temperature 3: 97 percent / 10 percent aq. HCl / dioxane / 1 h / Heating View Scheme

1: 97 percent / methanol; tetrahydrofuran / 1.) 0 deg C, 0.5 h, 2.) room temperature, 12 h 2: 76 percent / 10 percent aq. HCl / 0.5 h / Ambient temperature 3: 97 percent / 10 percent aq. HCl / dioxane / 1 h / Heating 4: SOCl2 / 5 h / Heating 5: 95 percent / Et3N / CH2Cl2 / 12 h / Heating View Scheme