4,5-二氢-2-苯基恶唑合成路线 (共 96 条)
反应条件
1: 60 percent / nitromethane / 12 h / 60 - 70 °C 2: 70 percent / acetonitrile / RT, 2 h, then reflux, 6 h View Scheme
参考文献
Tetrahedron, , vol. 42, # 5 p. 1449 - 1460
参考文献
Mundy, Bradford P.; Kim, Youseung
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 1221 - 1222
反应条件
phosphorus pentachloride
参考文献
Chemische Berichte, , vol. 25, p. 3048
反应条件
orthoformic acid triethyl ester 2 h; Heating;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2328 - 2332
参考文献
Angewandte Chemie, , vol. 78, # 20 p. 913 - 927
反应条件
tetrachloromethane; triethylamine; triphenylphosphine 1.) acetonitrile, 2 h, 2 deg C, 2.) acetonitrile, 20 min, 2 - 11 deg C; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Tetrahedron, , vol. 49, # 41 p. 9353 - 9372
反应条件
1: 77 percent / Heating 2: 1) thionylchloride, 2) aqueous potassium hydroxide / 1) 0 deg C, 1 h, 2) reflux, 8 h. View Scheme
参考文献
Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 20, # 7 p. 713 - 716
Khimiya Geterotsiklicheskikh Soedinenii, , vol. 20, # 7 p. 881 - 884
反应条件
2: ethanolic sodium ethylate View Scheme
参考文献
Journal of the Chemical Society, , p. 1919,1925
参考文献
Journal of the Chemical Society, , p. 1919,1925
参考文献
Journal of the Chemical Society, , p. 1100