4,5-二氢-2-苯基恶唑合成路线 （共 96 条）
反应条件
1: trimethylsilylazide / methanol / 0.17 h / 140 °C / Microwave irradiation
2: palladium 10 on activated carbon; hydrogen / methanol / 20 °C / 750.08 Torr
View Scheme
参考文献
Gutmann, Bernhard; Roduit, Jean-Paul; Roberge, Dominique; Kappe, C. Oliver
Chemistry - A European Journal, 2011 , vol. 17, # 47 p. 13146 - 13150
反应条件
sodium hydrogencarbonate
参考文献
Goldberg; Kelly
Journal of the Chemical Society, 1948 , p. 1919,1925
参考文献
Tomalia,D.A.; Paige,J.N.
Journal of Organic Chemistry, 1973 , vol. 38, # 3 p. 422 - 430
反应条件
trimethylsilylazide in methanol
T=140°C; 0.166667 h; Microwave irradiation;
参考文献
Gutmann, Bernhard; Roduit, Jean-Paul; Roberge, Dominique; Kappe, C. Oliver
Chemistry - A European Journal, 2011 , vol. 17, # 47 p. 13146 - 13150
参考文献
Leffler; Adams
Journal of the American Chemical Society, 1937 , vol. 59, p. 2252,2256
反应条件
1: 56 percent / nickel peroxide / benzene / 15 h / Heating
2: α-picoline, nitronium tetrafluoroborate / acetonitrile / 4 h / 20 °C
View Scheme
参考文献
Belen'kii, L. I.; Cheskis, M. A.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1984 , vol. 20, # 7 p. 713 - 716
Khimiya Geterotsiklicheskikh Soedinenii, 1984 , vol. 20, # 7 p. 881 - 884
反应条件
1: 56 percent / nickel peroxide / benzene / 15 h / Heating
2: 9 percent / 1) bromine, 2) triethylamine / benzene / 7 h / Heating
View Scheme
参考文献
Belen'kii, L. I.; Cheskis, M. A.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1984 , vol. 20, # 7 p. 713 - 716
Khimiya Geterotsiklicheskikh Soedinenii, 1984 , vol. 20, # 7 p. 881 - 884
反应条件
1: NaOCl, (Bu)4NHSO4 / ethyl acetate; H2O / 12 h
2: silica gel / CH2Cl2
View Scheme
参考文献
Levin, Jeremy I.; Weinreb, Steven M.
Tetrahedron Letters, 1982 , vol. 23, # 23 p. 2347 - 2350
反应条件
sodium hypochlorite; tetra(n-butyl)ammonium hydrogensulfate in water; ethyl acetate
12 h;
参考文献
Levin, Jeremy I.; Weinreb, Steven M.
Tetrahedron Letters, 1982 , vol. 23, # 23 p. 2347 - 2350
反应条件
sodium nitrite in water; acetic acid
T=25°C; 0.0333333 h;
参考文献
Loeppky, Richard N.; Cui, Wenge
Tetrahedron Letters, 1998 , vol. 39, # 14 p. 1845 - 1848
