5,6-二氯吲哚烷-2-酮合成路线 （共 7 条）
反应条件
hydrogen; acetic acid; platinum(IV) oxide T=20°C; Reduction; P=2068.65 Torr; 20 h;
参考文献
Chen, Jiong J.; Wei, Yuan; Drach, John C.; Townsend, Leroy B.
Journal of Medicinal Chemistry, 2000 , vol. 43, # 12 p. 2449 - 2456
反应条件
hydrogenchloride; tin in ethanol Heating;
参考文献
Kraynack, Erica A.; Dalgard, Jackline E.; Gaeta, Federico C. A.
Tetrahedron Letters, 1998 , vol. 39, # 42 p. 7679 - 7682
反应条件
1: 82 percent / concd H2SO4 / 7 h / Heating 2: 76 percent / H2; AcOH / PtO2 / 20 h / 20 °C / 2068.65 Torr View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 43, # 12 p. 2449 - 2456
反应条件
1: 97 percent / NaH / dimethylsulfoxide / 100 °C 2: 95 percent / Sn, HCl / ethanol / Heating View Scheme
参考文献
Tetrahedron Letters, , vol. 39, # 42 p. 7679 - 7682
反应条件
1H-imidazole; phosphorus oxytribromide in 1,2-dichloro-ethane Bromination; 2.5 h; Heating;
参考文献
Chen, Jiong J.; Wei, Yuan; Drach, John C.; Townsend, Leroy B.
Journal of Medicinal Chemistry, 2000 , vol. 43, # 12 p. 2449 - 2456
反应条件
1H-imidazole; trichlorophosphate in 1,2-dichloro-ethane Chlorination; 2.5 h; Heating;
参考文献
Chen, Jiong J.; Wei, Yuan; Drach, John C.; Townsend, Leroy B.
Journal of Medicinal Chemistry, 2000 , vol. 43, # 12 p. 2449 - 2456
反应条件
1: pyridine*HBr*Br2 / 2-methyl-propan-2-ol; H2O / 16 h 2: 70 percent / H2O / methanol / 50 h / Heating View Scheme
参考文献
Tetrahedron Letters, , vol. 39, # 42 p. 7679 - 7682
