3,4-二氢-6-(三甲基甲硅烷基氧基)-2H-吡喃合成路线 （共 7 条）
反应条件
methyl allyl carbonate; palladium diacetate in acetonitrile Heating;
参考文献
Minami, Ichiro; Takahashi, Kazuhiko; Shimizu, Isao; Kimura, Tsuneo; Tsuji, Jiro
Tetrahedron, 1986 , vol. 42, # 11 p. 2971 - 2978
反应条件
1: trifluoromethanesulfonyloxybenzene With dicyclohexyl(2′,6′-dimethoxybiphenyl-2-yl)phosphine; anhydrous lithium acetate; palladium diacetate in tert-butyl methyl ether T=25°C; 0.166667 h; Inert atmosphereGloveboxSchlenk technique; 2: ((3,4-dihydro-2H-pyran-6-yl)oxy)trimethylsilane in tert-butyl methyl ether T=25°C; 6 h; Inert atmosphereGlovebox; enantioselective reaction;
参考文献
Huang, Zhiyan; Chen, Zuliang; Lim, Li Hui; Quang, Gia Chuong Phan; Hirao, Hajime; Zhou, Jianrong
Angewandte Chemie - International Edition, 2013 , vol. 52, # 22 p. 5807 - 5812
Angew. Chem., 2013 , vol. 125, # 22 p. 5919 - 5924
反应条件
lithium diisopropyl amide in tetrahydrofuran
T=-78°C; 0.5 h;
参考文献
Paterson, Ian
Tetrahedron, 1988 , vol. 44, # 13 p. 4207 - 4220
反应条件
zinc dibromide in dichloromethane
T=20°C; 16 h;
参考文献
Paterson, Ian
Tetrahedron, 1988 , vol. 44, # 13 p. 4207 - 4220
反应条件
triethylamine hydrofluoric acid in benzene
1.) 30 min, RT, 2.) 5-10 h, RT;
参考文献
Rubottom, George M.; Gruber, John M.; Marrero, Roberto; Juve, Henrik D.; Kim, Wan Chong
Journal of Organic Chemistry, 1983 , vol. 48, # 25 p. 4940 - 4944
反应条件
1: 96 percent / ZnBr2 / CH2Cl2 / 20 °C
2: 1.) sodium metaperiodate / 1.) MeOH-H2O (9:1), 20 deg C, 16 h; 2.) CCl4, 45 deg C, 1 h
View Scheme
参考文献
Paterson, Ian
Tetrahedron, 1988 , vol. 44, # 13 p. 4207 - 4220
反应条件
4 A molecular sieve; titanium tetrachloride in dichloromethane
T=-78 - 23°C; Mikaiyama-Claisen reaction; 21.5 h;
参考文献
Christoffers, Jens; Oertling, Heiko; Fischer, Peter; Frey, Wolfgang
Tetrahedron, 2003 , vol. 59, # 21 p. 3769 - 3778
