5-(3-氟苯基)-2-甲基-吡啶合成路线 （共 3 条）
反应条件
potassium carbonate; tetrakis(triphenylphosphine) palladium(0) in ethanol; water; toluene T=120°C; 22 h;
参考文献
Lee, Sunkyung; Song, Jong-Hwan; Park, Chul Min; Kim, Jin-Seok; Jeong, Ji-Hye; Cho, Woo-Young; Lim, Dong-Chul
ACS Medicinal Chemistry Letters, 2013 , vol. 4, # 11 p. 1054 - 1058
反应条件
potassium phosphate; {2-[2-(di(2-naphthyloxy)phosphinoxy)-3,5-bis(tert-butyl)phenyl]-4,6-bis(tert-butyl)phenoxy}di(2-naphthyloxy)phosphine; (1,5-cyclo-octadiene) nickel complexes in toluene T=80°C; 6 h;
参考文献
Mitsubishi Chemical Corporation
Patent: JP2005/82526 A, 2005 ;
Location in patent: Page/Page column 25 ;
反应条件
1: pyridine / dichloromethane / 1.5 h / 0 °C 2: potassium carbonate / tetrakis(triphenylphosphine) palladium(0) / toluene; ethanol; water / 22 h / 120 °C View Scheme
参考文献
WO2011/162562 A2, ;
WO 2011/162562 A2
