2-氯-1H-吲哚(9ci)合成路线 （共 7 条）
反应条件
N,N-diethylaniline; trichlorophosphate in toluene
T=20°C; 3 h; Heating / reflux;
参考文献
UCB S.A.
Patent: WO2006/128692 A2, 2006 ;
Location in patent: Page/Page column 125; 126 ;
反应条件
caesium carbonate in N,N-dimethyl-formamide
T=110°C; 8 h; Green chemistry;
参考文献
Li, Pinhua; Ji, Yong; Chen, Wei; Zhang, Xiuli; Wang, Lei
RSC Advances, 2013 , vol. 3, # 1 p. 73 - 78
反应条件
tetrabutyl-ammonium chloride in N,N-dimethyl-formamide
T=100°C; 2 h;
参考文献
Budylin, V. A.; Ermolenko, M. S.; Chugtai, F. A.; Kost, A. N.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1981 , vol. 17, # 11 p. 1088 - 1090
Khimiya Geterotsiklicheskikh Soedinenii, 1981 , vol. 17, # 11 p. 1494 - 1496
反应条件
1: With n-butyllithium in toluene
2: With 1,2,2-trichloro-1,1,2-trichloro-ethane in toluene
参考文献
Herbert, John M.; Maggiani, Maria
Synthetic Communications, 2001 , vol. 31, # 6 p. 947 - 951
反应条件
1: 75 percent / Hydrochloric acid (36percent) / ethanol / 0.5 h / -15 °C
2: 70 percent / dimethylsulfoxide / 2 h / 100 °C
View Scheme
参考文献
Budylin, V. A.; Ermolenko, M. S.; Chugtai, F. A.; Sharbatyan, P. A.; Kost, A. N.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1981 , vol. 17, # 11 p. 1095 - 1097
Khimiya Geterotsiklicheskikh Soedinenii, 1981 , vol. 17, # 11 p. 1503 - 1505
反应条件
Yield given. Multistep reaction;
参考文献
Bergman, Jan; Venemalm, Lennart
Journal of Organic Chemistry, 1992 , vol. 57, # 8 p. 2495 - 2497
反应条件
lithium chloride in N,N-dimethyl-formamide
T=100°C; 2 h; 1)diff. lithium or ammonium halides 2) in the presence of 15-crown-5 ether; Product distribution;
参考文献
Budylin, V. A.; Ermolenko, M. S.; Chugtai, F. A.; Kost, A. N.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1981 , vol. 17, # 11 p. 1088 - 1090
Khimiya Geterotsiklicheskikh Soedinenii, 1981 , vol. 17, # 11 p. 1494 - 1496
