N-苄基-2-氯嘧啶-4-胺合成路线 （共 3 条）
反应条件
N-ethyl-N,N-diisopropylamine in ethanol
T=0 - 80°C; 3.08333 h;
参考文献
Mohamed, Tarek; Zhao, Xiaobei; Habib, Lila K.; Yang, Jerry; Rao, Praveen P.N.
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 7 p. 2269 - 2281
反应条件
N-ethyl-N,N-diisopropylamine in isopropyl alcohol
T=20°C; 8.5 h; Cooling with ice;
参考文献
Chen, Kuen-Feng; Pao, Kuan-Chuan; Su, Jung-Chen; Chou, Yi-Chieh; Liu, Chun-Yu; Chen, Hui-Ju; Huang, Jui-Wen; Kim, Inki; Shiau, Chung-Wai
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 20 p. 6144 - 6153
反应条件
triethylamine in tetrahydrofuran
T=110°C; 1.25 h; Microwave irradiation; Overall yield = 91 percent;
参考文献
Coombs, Thomas C.; Tanega, Cordelle; Shen, Min; Wang, Jenna L.; Auld, Douglas S.; Gerritz, Samuel W.; Schoenen, Frank J.; Thomas, Craig J.; Aube, Jeffrey
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 12 p. 3654 - 3661
