氧代[(苯基甲基)氨基]乙酸乙酯合成路线 （共 13 条）
反应条件
1: ethanol / 3 h
2: lithium aluminum hydride / tetrahydrofuran / 16 h / Heating
View Scheme
参考文献
Lambert, Joseph B.; Huseland, Dave E.; Wang, Gen-tai
Synthesis, 1986 , # 8 p. 657 - 658
反应条件
sodium hydroxide in tetrahydrofuran; water
参考文献
Perni, Robert B.; Chandorkar, Gurudatt; Cottrell, Kevin M.; Gates, Cynthia A.; Lin, Chao; Lin, Kai; Luong, Yu-Ping; Maxwell, John P.; Murcko, Mark A.; Pitlik, Janos; Rao, Govinda; Schairer, Wayne C.; Drie, John Van; Wei, Yunyi
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 12 p. 3406 - 3411
反应条件
1: PCl5, pyridine / CH2Cl2 / 1 h / Ambient temperature
2: hydrazoic acid / CH2Cl2; benzene / 1.) RT, 1 h, 2.) reflux, 5 h
3: 90 percent / KOH / ethanol
4: oxalyl chloride, pyridine / benzene / 0.5 h / 15 °C
View Scheme
参考文献
Klaubert, Dieter H.; Sellstedt, John H.; Guinosso, Charles J.; Bell, Stanley C.; Capetola, Robert J.
Journal of Medicinal Chemistry, 1981 , vol. 24, # 6 p. 748 - 752
