1: chloroacetic acid With potassium carbonate in N,N-dimethyl-formamide 2: 2-(4-bromophenyl)ethanenitrile With potassium hydroxide in N,N-dimethyl-formamide T=20 - 25°C; 2 h; 3: With sodium hydroxide 16 h; Heating;

1: NaOEt / ethanol 2: (i) EtOH, (ii) aq. HCl View Scheme

sodium hydroxide; TiCl3 2.) cetone, 20 deg C, 2 h; Yield given. Multistep reaction;

(i) EtOH, (ii) aq. HCl; Multistep reaction;