(3S)-3-(羟甲基)吗啉-4-羧酸叔丁酯合成路线 （共 4 条）
反应条件
1: With tetrahydrofuran; borane T=0 - 20°C; 4.25 h; 2: With water; acetic acid in tetrahydrofuran 1 h; 3: With sodium hydrogencarbonate in tetrahydrofuran; water
参考文献
WO2006/105262 A1, ;
Page/Page column 70 ;
反应条件
triethylamine in methanol T=20°C; 1 h;
参考文献
Dave, Rajesh; Sasaki, N. Andre
Tetrahedron Asymmetry, 2006 , vol. 17, # 3 p. 388 - 401
反应条件
1: 87 percent / TBAF / tetrahydrofuran 2: 97 percent / Et3N / methanol / 1 h / 20 °C View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 17, # 3 p. 388 - 401
反应条件
2,2,6,6-tetramethyl-piperidine-N-oxyl; sodium hypochlorite; sodium hydrogencarbonate; potassium bromide in acetone T=0°C; 2 h;
参考文献
Tetrahedron Asymmetry, , vol. 17, # 3 p. 388 - 401
