2,2-二氟-1-(1-萘基)乙酮合成路线 （共 6 条）
反应条件
1: With chloro-trimethyl-silane in methanol
T=0 - 20°C; Inert atmosphere;
2: With water; sodium hydroxide in methanol
Inert atmosphere;
参考文献
Katz, Jason D.; Lapointe, Blair T.; Dinsmore, Christopher J.
Journal of Organic Chemistry, 2009 , vol. 74, # 22 p. 8866 - 8869
反应条件
hydrogenchloride
T=20°C;
参考文献
Surya Prakash; Hu; Olah
Journal of Fluorine Chemistry, 2001 , vol. 112, # 2 p. 357 - 362
反应条件
1: Mg / tetrahydrofuran / 2 h / 0 °C
2: aq. HCl / 20 °C
View Scheme
参考文献
Surya Prakash; Hu; Olah
Journal of Fluorine Chemistry, 2001 , vol. 112, # 2 p. 357 - 362
反应条件
hydrogenchloride; water
参考文献
Krane Thvedt, Thor Hakon; Fuglseth, Erik; Sundby, Eirik; Hoff, Bard Helge
Tetrahedron, 2009 , vol. 65, # 46 p. 9550 - 9556
反应条件
(i) nBuLi, Et2O, (ii) /BRN= 1756873/; Multistep reaction;
参考文献
Kazennikova,G.V. et al.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1961 , p. 772 - 774
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1961 , p. 835 - 838
反应条件
1: Mg / tetrahydrofuran / 2 h / 0 °C
2: aq. HCl / 20 °C
View Scheme
参考文献
Surya Prakash; Hu; Olah
Journal of Fluorine Chemistry, 2001 , vol. 112, # 2 p. 357 - 362
