a,3-二甲基-5-异噁唑甲醇合成路线 （共 9 条）
反应条件
1: pyridinium chlorochromate; sodium acetate / CH2Cl2 / 20 °C 2: phenyltrimethylammonium tribromide / tetrahydrofuran / 25 °C View Scheme
参考文献
De Amici; Conti; Dallanoce; Kassi; Castellano; Stefancich; De Micheli
Medicinal Chemistry Research, 2000 , vol. 10, # 2 p. 69 - 80
反应条件
1: With hydrogen; palladium on activated charcoal in methanol 10 h; 2: With hydrogenchloride in water 3 h;
参考文献
Chimichi, Stefano; Boccalini, Marco; Cosimelli, Barbara; Dall'Acqua, Francesco; Viola, Giampietro
Tetrahedron, 2003 , vol. 59, # 28 p. 5215 - 5223
反应条件
sodium hypochlorite; triethylamine in dichloromethane; water
Ambient temperature;
参考文献
Felman; Jirkovsky; Memoli; Borella; Wells; Russell; Ward
Journal of Medicinal Chemistry, 1992 , vol. 35, # 7 p. 1183 - 1190
反应条件
sodium tetrahydroborate in ethanol
T=-10 - 20°C;
参考文献
Chimichi, Stefano; Boccalini, Marco; Cosimelli, Barbara; Dall'Acqua, Francesco; Viola, Giampietro
Tetrahedron, 2003 , vol. 59, # 28 p. 5215 - 5223
反应条件
triethylamine; trichlorophosphate in chloroform
T=10 - 20°C;
参考文献
Chimichi, Stefano; Boccalini, Marco; Cosimelli, Barbara; Dall'Acqua, Francesco; Viola, Giampietro
Tetrahedron, 2003 , vol. 59, # 28 p. 5215 - 5223
反应条件
sodium hypochlorite; triethylamine in chloroform; water
T=0 - 4°C;
参考文献
Chimichi, Stefano; Boccalini, Marco; Cosimelli, Barbara; Dall'Acqua, Francesco; Viola, Giampietro
Tetrahedron, 2003 , vol. 59, # 28 p. 5215 - 5223
反应条件
sodium hydrogencarbonate in ethyl acetate
T=20°C;
参考文献
De Amici; Conti; Dallanoce; Kassi; Castellano; Stefancich; De Micheli
Medicinal Chemistry Research, 2000 , vol. 10, # 2 p. 69 - 80
反应条件
hydroxylamine hydrochloride; sodium acetate in ethanol
24 h; Heating; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Deshayes, Christian; Chabannet, Michel; Gelin, Suzanne
Synthesis, 1984 , # 10 p. 868 - 870
反应条件
chromium(VI) oxide; sulfuric acid in water; acetone
T=0 - 20°C;
参考文献
Felman; Jirkovsky; Memoli; Borella; Wells; Russell; Ward
Journal of Medicinal Chemistry, 1992 , vol. 35, # 7 p. 1183 - 1190
