3-甲氧基-4-甲基苯甲酸合成路线 （共 34 条）
反应条件
acetic acid in diethyl ether
参考文献
Irie; Matsumoto; Nishimura; Zhang
Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 7 p. 1852 - 1856
反应条件
acetyl chloride 36 h;
参考文献
Goverdhan, Gilla; Reddy, Anumula Raghupathi; Sampath, Aalla; Srinivas, Kurella; Himabindu, Vurimidi; Reddy, Ghanta Mahesh
Organic Process Research and Development, 2009 , vol. 13, # 1 p. 67 - 72
反应条件
in methanol; ethyl acetate
参考文献
Pfizer Inc.
Patent: US5280039 A1, 1994 ;
反应条件
nitric acid; acetic anhydride
参考文献
Simonsen; Rau
Journal of the Chemical Society, 1921 , vol. 119, p. 1341 Anm.
参考文献
Simonsen; Rau
Journal of the Chemical Society, 1921 , vol. 119, p. 1341 Anm.
反应条件
chlorosulphonyl isocyanate in dichloromethane 0.75 h; Heating / reflux;
参考文献
NOVARTIS AG; NOVARTIS PHARMA GMBH
Patent: WO2007/139992 A2, 2007 ;
Location in patent: Page/Page column 41-42 ;
WO 2007/139992 A2
反应条件
in dichloromethane; N,N-dimethyl-formamide
参考文献
ICI AMERICAS INC.
Patent: EP199543 B1, 1991 ;
反应条件
1: 98 percent / acetyl chloride / 36 h 2: 64 percent / bromine / CCl4 / 4 h / Irradiation View Scheme
参考文献
Brown, Frederick J.; Yee, Ying K.; Cronk, Laura A.; Hebbel, Kevin C.; Krell, Robert D.; Snyder, David W.
Journal of Medicinal Chemistry, 1990 , vol. 33, # 6 p. 1771 - 1781
反应条件
1: LiAlH4 2: SOCl2 3: dimethylformamide View Scheme
参考文献
Valenta; Protiva
Collection of Czechoslovak Chemical Communications, 1977 , vol. 42, # 7 p. 2240 - 2245
反应条件
aluminum tri-bromide; benzene
参考文献
Brown; Newbold
Journal of the Chemical Society, 1953 , p. 1285,1287
