3-溴-2,3-二氢-1H-吡咯并[2,1-b]喹唑啉-9-酮合成路线 （共 7 条）
反应条件
Amberlyst A-26 Br3(-) form in tetrahydrofuran
T=20°C;
参考文献
Kamal, Ahmed; Devaiah; Shankaraiah; Laxma Reddy
Synlett, 2006 , # 16 p. 2609 - 2612
反应条件
N-bromosuccinmide in acetic acid
T=85°C; 4 h;
参考文献
D'yakonov, A. L.; Telezhenetskaya, M. V.; Tashkodzhaev, B.
Chemistry of Natural Compounds, 1992 , vol. 28, # 2 p. 200 - 206
Khimiya Prirodnykh Soedinenii, 1992 , # 2 p. 233 - 240
反应条件
1: SOCl2 / benzene; dimethylformamide / 5 h / 20 °C
2: Et3N / tetrahydrofuran / 2 h
3: NaI; TMSCl / acetonitrile / 0.25 h / 20 °C
4: 52 percent / NBS; benzoyl peroxide / CCl4 / 5 h / Heating
View Scheme
参考文献
Kamal; Ramana; Rao
Journal of Organic Chemistry, 2001 , vol. 66, # 3 p. 997 - 1001
反应条件
1: Et3N / tetrahydrofuran / 2 h
2: NaI; TMSCl / acetonitrile / 0.25 h / 20 °C
3: 52 percent / NBS; benzoyl peroxide / CCl4 / 5 h / Heating
View Scheme
参考文献
Kamal; Ramana; Rao
Journal of Organic Chemistry, 2001 , vol. 66, # 3 p. 997 - 1001
反应条件
1: NaI; TMSCl / acetonitrile / 0.25 h / 20 °C
2: 52 percent / NBS; benzoyl peroxide / CCl4 / 5 h / Heating
View Scheme
参考文献
Kamal; Ramana; Rao
Journal of Organic Chemistry, 2001 , vol. 66, # 3 p. 997 - 1001
反应条件
phosphorus tribromide in benzene
5 h; Heating;
参考文献
Telezhenetskaya, M. V.; D'yakonov, A. L.
Chemistry of Natural Compounds, 1991 , vol. 27, # 4 p. 471 - 474
Khimiya Prirodnykh Soedinenii, 1991 , # 4 p. 541 - 545
反应条件
1: 90 percent / 18-crown-6 / acetonitrile / 1 h / 20 °C
2: lipase PS / acetonitrile / 7 h / 20 °C / pH 7.0
3: NaOH / H2O; methanol; ethyl acetate / 0.25 h / 0 °C
View Scheme
参考文献
Kamal; Ramana; Rao
Journal of Organic Chemistry, 2001 , vol. 66, # 3 p. 997 - 1001
