N-(4-苯基-2-噻唑基)十二碳酰胺合成路线 (共 3 条)
反应条件
4-(N,N-dimethlyamino)pyridine in dichloromethane
T=0 - 20°C; 2 h; Inert atmosphere;
参考文献
Zheng, Shilong; Zhong, Qiu; Jiang, Quan; Mottamal, Madhusoodanan; Zhang, Qiang; Zhu, Naijue; Burow, Matthew E.; Worthylake, Rebecca A.; Wang, Guangdi
ACS Medicinal Chemistry Letters, 2013 , vol. 4, # 2 p. 191 - 196
反应条件
1: ethanol / 1 h / |Reflux
2: 4-(N,N-dimethlyamino)pyridine / dichloromethane / 2 h / 0 - 20 °C / |Inert atmosphere
View Scheme
参考文献
Zheng, Shilong; Zhong, Qiu; Jiang, Quan; Mottamal, Madhusoodanan; Zhang, Qiang; Zhu, Naijue; Burow, Matthew E.; Worthylake, Rebecca A.; Wang, Guangdi
ACS Medicinal Chemistry Letters, 2013 , vol. 4, # 2 p. 191 - 196
反应条件
1: thionyl chloride / 2 h / |Reflux
2: 4-(N,N-dimethlyamino)pyridine / dichloromethane / 2 h / 0 - 20 °C / |Inert atmosphere
View Scheme
参考文献
Zheng, Shilong; Zhong, Qiu; Jiang, Quan; Mottamal, Madhusoodanan; Zhang, Qiang; Zhu, Naijue; Burow, Matthew E.; Worthylake, Rebecca A.; Wang, Guangdi
ACS Medicinal Chemistry Letters, 2013 , vol. 4, # 2 p. 191 - 196