顺-(1R,2S)-(+)-苄胺环己烷甲醇合成路线 （共 19 条）
反应条件
sodium; isopropyl alcohol in tetrahydrofuran T=0°C;
参考文献
Journal of Organic Chemistry, , vol. 59, # 18 p. 5328 - 5335
反应条件
lithium aluminium tetrahydride in diethyl ether 1.) RT, 30 min, 2.) reflux, 3 h;
参考文献
Goodridge, Richard J.; Hambley, Trevor W.; Ridley, Damon D.
Australian Journal of Chemistry, 1986 , vol. 39, # 4 p. 591 - 604
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
参考文献
Gera, L.; Bernath, G.; Sohar, P.
Acta Chimica Academiae Scientiarum Hungaricae, 1980 , vol. 105, # 4 p. 293 - 302
反应条件
1: 4 percent / NaBH(OAc)3 / acetic acid / 6 h / 10 °C 2: 73 percent / LiAlH4 / diethyl ether / 15 h / Ambient temperature View Scheme
参考文献
Journal of Organic Chemistry, , vol. 59, # 18 p. 5328 - 5335
反应条件
lithium aluminium tetrahydride
参考文献
Gera, L.; Bernath, G.; Sohar, P.
Acta Chimica Academiae Scientiarum Hungaricae, 1980 , vol. 105, # 4 p. 293 - 302
反应条件
1: 99 percent / Na(OAc)3BH; glac. AcOH / CH2Cl2 / 18 h 2: 90 percent / Vitride / tetrahydrofuran / 2 h / 20 °C View Scheme
参考文献
Organic Preparations and Procedures International, , vol. 24, # 6 p. 685 - 687
反应条件
1: 99 percent / Na(OAc)3BH; glac. AcOH / CH2Cl2 / 18 h 2: 90 percent / Vitride / tetrahydrofuran / 2 h / 20 °C View Scheme
参考文献
Organic Preparations and Procedures International, , vol. 24, # 6 p. 685 - 687
反应条件
1: HCl / 3 h / Heating 2: 80 percent / benzene / 3 h / Heating 3: 84 percent / LiAlH4 / diethyl ether / 1.) RT, 30 min, 2.) reflux, 3 h View Scheme
参考文献
Australian Journal of Chemistry, , vol. 39, # 4 p. 591 - 604
反应条件
1: 80 percent / benzene / 3 h / Heating 2: 84 percent / LiAlH4 / diethyl ether / 1.) RT, 30 min, 2.) reflux, 3 h View Scheme
参考文献
Australian Journal of Chemistry, , vol. 39, # 4 p. 591 - 604
反应条件
1: 3 M aq. HCl / 5 h / Heating 2: HCl / 3 h / Heating 3: 80 percent / benzene / 3 h / Heating 4: 84 percent / LiAlH4 / diethyl ether / 1.) RT, 30 min, 2.) reflux, 3 h View Scheme
参考文献
Australian Journal of Chemistry, , vol. 39, # 4 p. 591 - 604
