六氢-3-(3-羟基苯基)-1-甲基-2H-氮杂卓-2-酮合成路线 （共 14 条）
参考文献
John Wyeth and Brother Limited
Patent: US4296029 A1, 1981 ;
反应条件
1: 90 percent / aq. sodium hydroxide / Ambient temperature
2: 1.) sodium amide / 1.) toluene, reflux, 2 h, 2.) THF, 2 h
View Scheme
参考文献
Bradley; Cavalla; Edington; et al.
European Journal of Medicinal Chemistry, 1980 , vol. 15, # 4 p. 375 - 385
反应条件
1: 90 percent / aq. sodium hydroxide / Ambient temperature
2: 1.) sodium amide / 1.) toluene, reflux, 2 h, 2.) THF, 2 h
3: 84 percent / lithium aluminium hydride / tetrahydrofuran / 2 h / Heating
View Scheme
参考文献
Bradley; Cavalla; Edington; et al.
European Journal of Medicinal Chemistry, 1980 , vol. 15, # 4 p. 375 - 385
反应条件
sodium hydroxide
Ambient temperature;
参考文献
Bradley; Cavalla; Edington; et al.
European Journal of Medicinal Chemistry, 1980 , vol. 15, # 4 p. 375 - 385
