2-(2-吡啶)苯并噻唑合成路线 （共 40 条）
反应条件
1: dimethylformamide
2: 0.5 h / 225 °C
View Scheme
参考文献
Babichev,F.S. et al.
Sov. Prog. Chem. (Engl. Transl.), 1966 , vol. 32, p. 706 - 715,542 - 550
参考文献
Emmert; Groll
Chemische Berichte, 1953 , vol. 86, p. 208,211
参考文献
Subarowskii; Woronina
Zhurnal Obshchei Khimii, 1953 , vol. 23, p. 140,142; engl. Ausg. S. 139, 140
参考文献
Emmert; Groll
Chemische Berichte, 1953 , vol. 86, p. 208,211
参考文献
E. Lilly and Co.
Patent: US2780628 , 1955 ;
反应条件
1: HNO3 / 2 h / Ambient temperature
2: SnCl2, conc. HCl / 1 h / Heating
3: triethylamine / tetrahydrofuran / 3 h / Ambient temperature
View Scheme
参考文献
Haugwitz; Angel; Jacobs; Maurer; Narayanan; Cruthers; Szanto
Journal of Medicinal Chemistry, 1982 , vol. 25, # 8 p. 969 - 974
反应条件
nitric acid in sulfuric acid
2 h; Ambient temperature; Title compound not separated from byproducts;
参考文献
Haugwitz; Angel; Jacobs; Maurer; Narayanan; Cruthers; Szanto
Journal of Medicinal Chemistry, 1982 , vol. 25, # 8 p. 969 - 974
反应条件
nitric acid
2 h; Ambient temperature; Title compound not separated from byproducts;
参考文献
Haugwitz; Angel; Jacobs; Maurer; Narayanan; Cruthers; Szanto
Journal of Medicinal Chemistry, 1982 , vol. 25, # 8 p. 969 - 974
反应条件
1: HNO3 / 2 h / Ambient temperature
2: SnCl2, conc. HCl / 1 h / Heating
View Scheme
参考文献
Haugwitz; Angel; Jacobs; Maurer; Narayanan; Cruthers; Szanto
Journal of Medicinal Chemistry, 1982 , vol. 25, # 8 p. 969 - 974
反应条件
1: With zinc diacetate in methanol; water
0.5 h;
2: With sodium tetrahydroborate in methanol; water
0.25 h;
3: With hydrogen sulfide in methanol; water
0.166667 h;
参考文献
Dhillon, Harmeet; Singh, Urvasini; Pooja; Kumbhat, Sunita
Indian Journal of Chemistry - Section A Inorganic, Physical, Theoretical and Analytical Chemistry, 2008 , vol. 47, # 10 p. 1508 - 1511
