1: 53 percent / CSI / CH2Cl2; acetonitrile / 2.5 h / -42 °C 2: 97 percent / iodic acid/iodine, conc. sulfuric acid / CCl4; H2O; acetic acid / 24 h / Ambient temperature 3: 99.5 percent / NaOH, tetrabutylammonium hydrogen sulfate / CH2Cl2 / 2 h / 0 °C 4: 31.2 percent / triethylamine, palladium(II) acetate / acetonitrile / 0.67 h / 99 - 100 °C 5: 91.5 percent / NaOH, tetrabutylammonium hydrogen sulfate / CH2Cl2 / 2 h / 0 °C 6: hydrogen / PtO2 / 6 h / Ambient temperature 7: potassium hydroxide / aq. acetic acid / 4 h / 0 °C View Scheme

1: With sodium hydroxide in methanol; water 2: With hydrogenchloride in methanol; water