甲基4-异丙基-1H-吡咯-2-羧酸酯合成路线 （共 5 条）
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in toluene
4 h; Heating / reflux;
参考文献
ADDEX PHARMACEUTICALS SA
Patent: WO2006/123257 A2, 2006 ;
Location in patent: Page/Page column 78 ;
WO 2006/123257 A2
反应条件
1: 2 h / 100 °C
2: CH3ONa / methanol / 2 h / Heating
View Scheme
参考文献
Walizei, Gul Hassan; Breitmaier, Eberhard
Synthesis, 1989 , # 4 p. 337 - 340
反应条件
gallium(III) chloride
参考文献
Elmore; Dodson; Muttucumaru; Halford; Parry; Mottram
Food Chemistry, 2010 , vol. 122, # 3 p. 753 - 760
参考文献
Sugawa et al.
Yakugaku Zasshi, 1955 , vol. 75, p. 845,849
Chem.Abstr., 1956 , p. 4119
反应条件
1: potassium; benzene / Erwaermen des Kalium-Salzes mit Chlorokohlensaeure-aethylester
2: platinum; aq.-ethanolic HCl / Hydrogenation
3: aqueous HBr
4: ethanolic HCl
View Scheme
参考文献
Umio; Mizuno
Yakugaku Zasshi, 1957 , vol. 77, p. 421,424
Chem.Abstr., 1957 , p. 12069
