反应条件
1: 85 percent / diisopropylethylamine / 18 h / 150 °C / other reaction conditions 2: 1.) LiAlH4, 2.) H2O / 1.)Et2O, 2 h 3: methyltriphenoxyphosphonium iodide 4: 2.) NH4Cl/NH4OH / 1.) HMPA, THF, 70 deg C, 3 h, 2.) -40 deg C 5: 1.) t-butyllithium, 2.) NH4Cl/NH4OH / 1.) THF, from -78 deg C to 25 deg C and 15 min at room temperature, 2.) 40 deg C, H2O 6: BF3 etherate / diethyl ether 7: 30 percent / aq. 3N HCl View Scheme
参考文献
Genet, Jean Pierre; Kahn, Philippe
Tetrahedron Letters, 1980 , vol. 21, p. 1521 - 1524
