1: With [2,2']bipyridinyl; trimethylsilyl trifluoromethanesulfonate in dichloromethane
T=0°C; 0.5 h; Inert atmosphere;
2: With water in dichloromethane
T=20°C; 5 h; Inert atmosphere; chemoselective reaction;
1: With maleic anhydride; dihydrogen peroxide in water
T=46 - 49°C; Baeyer-Villiger Ketone Oxidation; 22 h;
2: With hydrogen in methanol; water
T=197°C; P=104192 Torr; 27 h; AutoclaveInert atmosphere;
参考文献
INVISTAD NORTH AMERICA S.A R.L.; HASTINGS, James D.; HERKES, Frank E.; RAJENDRAN, Gurusamy; SUN, Qun
Patent: WO2013/116029 A1, 2013 ;
Location in patent: Paragraph 00130 ;
1: 63 percent / potassium hydroxide / methanol / 1 h / Heating
2: conc. sulphuric acid / 16 h / Ambient temperature
View Scheme
参考文献
Bidd, Ilesh; Kelly, David J.; Ottley, Peter M.; Paynter, Oliver I.; Simmonds, Derek J.; Whiting, Mark C.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 7 p. 1369 - 1372