3-甲基-1H-1,2,4-噻唑合成路线 (共 12 条)
反应条件
potassium hydroxide in 1,4-dioxane
参考文献
Trzhtsinskaya, B. V.; Apakina, E. V.; Afonin, A. V.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1990 , vol. 39, # 4.2 p. 834 - 836
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1990 , # 4 p. 928 - 931
反应条件
sodium ethanolate in ethanol
8 h; Reflux;
参考文献
Gujjar, Ramesh; El Mazouni, Farah; White, Karen L.; White, John; Creason, Sharon; Shackleford, David M.; Deng, Xiaoyi; Charman, William N.; Bathurst, Ian; Burrows, Jeremy; Floyd, David M.; Matthews, David; Buckner, Frederick S.; Charman, Susan A.; Phillips, Margaret A.; Rathod, Pradipsinh K.
Journal of Medicinal Chemistry, 2011 , vol. 54, # 11 p. 3935 - 3949