1: 68 percent / H2SO4 / CHCl3; dioxane
2: 94 percent / NaI / acetone / 3 h / Heating
3: 93 percent / K2CO3 / dimethylformamide / 20 °C
4: 92 percent / TFA / 0.75 h / 20 °C
View Scheme
参考文献
Hardouin, Christophe; Kelso, Michael J.; Romero, F. Anthony; Rayl, Thomas J.; Leung, Donmienne; Hwang, Inkyu; Cravatt, Benjamin F.; Boger, Dale L.
Journal of Medicinal Chemistry, 2007 , vol. 50, # 14 p. 3359 - 3368
1: 94 percent / NaI / acetone / 3 h / Heating
2: 93 percent / K2CO3 / dimethylformamide / 20 °C
3: 92 percent / TFA / 0.75 h / 20 °C
View Scheme
参考文献
Hardouin, Christophe; Kelso, Michael J.; Romero, F. Anthony; Rayl, Thomas J.; Leung, Donmienne; Hwang, Inkyu; Cravatt, Benjamin F.; Boger, Dale L.
Journal of Medicinal Chemistry, 2007 , vol. 50, # 14 p. 3359 - 3368
1: 93 percent / K2CO3 / dimethylformamide / 20 °C
2: 92 percent / TFA / 0.75 h / 20 °C
View Scheme
参考文献
Hardouin, Christophe; Kelso, Michael J.; Romero, F. Anthony; Rayl, Thomas J.; Leung, Donmienne; Hwang, Inkyu; Cravatt, Benjamin F.; Boger, Dale L.
Journal of Medicinal Chemistry, 2007 , vol. 50, # 14 p. 3359 - 3368