1-(双环[2.2.1]庚-2-烯-2-基)乙酮合成路线 （共 9 条）
反应条件
potassium hydroxide; potassium permanganate
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 9, p. 391 - 403
反应条件
1: 81 percent / H2 / 10percent Pd/C / methanol / 18 h / 1551.4 Torr
2: 68 percent / Me3SiCl, NaI / acetonitrile / 14 h / Heating
3: 68 percent / Br2, red HgO, MgSO4 / CH2Cl2 / 3 h / Heating; Irradiation
4: 75 percent / 1,8-diazabicyclo<5.4.0>undec-7-ene / CHCl3 / 0.25 h / Heating
View Scheme
参考文献
Cornelius, Lyndon A. M.; Bone, Richard G. A.; Hastings, Riley H.; Deardorff, Matthew A.; Scharlach, Randall A.; et al.
Journal of Organic Chemistry, 1993 , vol. 58, # 11 p. 3188 - 3190
反应条件
toluene-4-sulfonic acid in acetone
6 h; Heating;
参考文献
Gottschalk, Franz-Josef; Weyerstahl, Peter
Chemische Berichte, 1980 , vol. 113, # 2 p. 555 - 565
反应条件
1: 76 percent / SnCl4 / CH2Cl2 / 15 h / Ambient temperature
2: 99 percent / H2 / Pd/C / methanol / Ambient temperature
3: 64 percent / p-TsOH / acetone / 6 h / Heating
View Scheme
参考文献
Gottschalk, Franz-Josef; Weyerstahl, Peter
Chemische Berichte, 1980 , vol. 113, # 2 p. 555 - 565
反应条件
1: 99 percent / H2 / Pd/C / methanol / Ambient temperature
2: 64 percent / p-TsOH / acetone / 6 h / Heating
View Scheme
参考文献
Gottschalk, Franz-Josef; Weyerstahl, Peter
Chemische Berichte, 1980 , vol. 113, # 2 p. 555 - 565
反应条件
1: 74 percent / diethyl ether / 80 h / Heating
2: AlCl3 / CH2Cl2 / 1.) room temperature, 5 min, 2.) -25 deg C, 10 min
View Scheme
参考文献
Nagendrappa, Gopalpur; Begum, Noor Shahina
Tetrahedron, 1999 , vol. 55, # 25 p. 7923 - 7934
反应条件
phosphorus pentoxide in benzene
Heating;
参考文献
Kagawa,M.
Chemical and Pharmaceutical Bulletin, 1961 , vol. 9, p. 391 - 403
反应条件
1: liq. NH3
2: P2O5 / benzene / Heating
View Scheme
参考文献
Kagawa,M.
Chemical and Pharmaceutical Bulletin, 1961 , vol. 9, p. 391 - 403
反应条件
aluminium trichloride in dichloromethane
1.) room temperature, 5 min, 2.) -25 deg C, 10 min; Yield givenYields of byproduct given;
参考文献
Nagendrappa, Gopalpur; Begum, Noor Shahina
Tetrahedron, 1999 , vol. 55, # 25 p. 7923 - 7934
