反应条件
1: N,N'-bis(3,4-dichlorophenyl)hydrazine With sodium ethanolate in ethanol
T=50°C;
2: diethyl malonate in ethanol
T=50 - 150°C; 1.5 h;
3: T=200°C; 3 h;
参考文献
Gilbert, Adam M.; Failli, Amedeo; Shumsky, Jay; Yang, Youjun; Severin, Anatoly; Singh, Guy; Hu, William; Keeney, David; Petersen, Peter J.; Katz, Alan H.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 20 p. 6027 - 6036
