3-溴-6-甲基吡啶-2-甲腈合成路线 (共 2 条)
反应条件
triethylamine in acetonitrile T=100°C;
参考文献
WO2009/111337 A1, ;
Page/Page column 177 ;
WO 2009/111337 A1
反应条件
(CuOTf)2.C6H6; trans-N,N'-dimethylcyclohexane-1,2-diamine; caesium carbonate in N,N-dimethyl-formamide T=120°C; 4 h; Inert atmosphere;
参考文献
GLAXO GROUP LIMITED; DI FABIO, Romano
Patent: WO2012/89606 A1, 2012 ;
Location in patent: Page/Page column 46-47 ;
WO 2012/089606 A1