3-溴-2-甲氧基-5-甲基吡啶合成路线 (共 3 条)
反应条件
silver carbonate in dichloromethane T=20°C;
参考文献
WO2008/141119 A2, ;
Page/Page column 96 ;
WO 2008/141119 A2
反应条件
in methanol T=65°C; 32 h; Inert atmosphere;
参考文献
WO2013/111105 A1, ;
Page/Page column 242; 243 ;
反应条件
potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in N,N-dimethyl-formamide T=80°C;
参考文献
VERTEX PHARMACEUTICALS INCORPORATED
Patent: WO2008/141119 A2, 2008 ;
Location in patent: Page/Page column 96 ;
WO 2008/141119 A2