1-三甲基硅-1,4-戊二炔合成路线 （共 3 条）
反应条件
magnesium Yield given. Multistep reaction;
参考文献
Journal of Organic Chemistry, , vol. 46, # 5 p. 881 - 885
参考文献
Synthesis, , p. 292 - 293
反应条件
1: 1.) ethylmagnesium bromide, copper(I) bromide / 1.) THF, -78 -> 25 deg C, 2.) -78 -> 25 deg C
2: H2 / Lindlar catalyst / hexane / 25 °C
3: KF / dimethylformamide / 25 °C
4: 90 percent / n-propylamine / tetrakis<triphenylphosphine>palladium, copper(I) iodide / benzene / 12 h / 25 °C
5: 60 percent / H2 / Lindlar catalyst / hexane / 25 °C
6: 75 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 25 °C
7: 90 percent / LiOH / tetrahydrofuran; H2O / 25 °C
View Scheme
参考文献
Nicolaou, K. C.; Ladduwahetty, T.; Taffer, I. M.; Zipkin, R. E.
Synthesis, 1986 , # 4 p. 344 - 347
