2-苯基-2-氰基丁酸乙酯合成路线 （共 19 条）
反应条件
potassium carbonate T=180°C; 47.5 h; Product distribution;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 10 p. 1323 - 1328
反应条件
(i), (ii) /BRN= 505934/; Multistep reaction;
参考文献
GB1434826 , ;
Chem.Abstr., , vol. 85, # 142852
反应条件
multistep reaction; influence of the ratio of the reactants on the yield and quality of the product;
参考文献
Pharmaceutical Chemistry Journal, , vol. 15, # 7 p. 512 - 515
Khimiko-Farmatsevticheskii Zhurnal, , vol. 15, # 7 p. 85 - 88
反应条件
sodium in ethanol various composition of reaction mixture; Product distribution;
参考文献
J. Appl. Chem. USSR (Engl. Transl.), , vol. 55, # 10 p. 2280 - 2285,2091 - 2094
参考文献
Egyt Gyogyszervegyeszeti Gyar
Patent: US4740228 A1, 1988 ;
反应条件
potassium hydroxide; N-benzyl-N,N,N-triethylammonium chloride in water T=45 - 50°C; Decarboxylation; 2 h;
参考文献
Glushkov; L'vov; Davydova; Kudinova; Polyakova; Sanzharova; Anisimova
Pharmaceutical Chemistry Journal, 1997 , vol. 31, # 3 p. 155 - 157
反应条件
sodium in ethanol various composition of reaction mixture; Product distribution;
参考文献
Sharkova, O. V.; Smirnova, G. E.; Shalygin, V. A.
J. Appl. Chem. USSR (Engl. Transl.), 1982 , vol. 55, # 10 p. 2280 - 2285,2091 - 2094
反应条件
potassium hydroxide in methanol T=15 - 20°C;
参考文献
Yin, Liang; Kanai, Motomu; Shibasaki, Masakatsu
Tetrahedron, 2012 , vol. 68, # 17 p. 3497 - 3506
反应条件
1: ethanol 2: aqueous HCl View Scheme
参考文献
Chamberlain et al.
Journal of the American Chemical Society, 1935 , vol. 57, p. 352
