sodium hydroxide 0.333333 h; Ambient temperature;

1: 22 percent / TMSOTf, molecular sieves 4 Angstroem / CH2Cl2; diethyl ether / 7.5 h 2: 41 percent / aq. 80percent AcOH / 40 h / 45 °C 3: 82 percent / 0.1N NaOH / CH2Cl2; methanol / 0.33 h / 0 °C 4: 95 percent / 0.1N NaOH / 0.33 h / Ambient temperature View Scheme

1: 22 percent / TMSOTf, molecular sieves 4 Angstroem / CH2Cl2; diethyl ether / 7.5 h 2: 41 percent / aq. 80percent AcOH / 40 h / 45 °C 3: 82 percent / 0.1N NaOH / CH2Cl2; methanol / 0.33 h / 0 °C 4: 95 percent / 0.1N NaOH / 0.33 h / Ambient temperature View Scheme

1: 82 percent / 0.1N NaOH / CH2Cl2; methanol / 0.33 h / 0 °C 2: 95 percent / 0.1N NaOH / 0.33 h / Ambient temperature View Scheme

1: 1.) NBS, AIBN; 2.) silica gel, H2O / 1.) CCl4; 2.) THF, r.t. 2: 22 percent / TMSOTf, molecular sieves 4 Angstroem / CH2Cl2; diethyl ether / 7.5 h 3: 41 percent / aq. 80percent AcOH / 40 h / 45 °C 4: 82 percent / 0.1N NaOH / CH2Cl2; methanol / 0.33 h / 0 °C 5: 95 percent / 0.1N NaOH / 0.33 h / Ambient temperature View Scheme

1: HgO(yellow), 20percent H2SO4 / tetrahydrofuran / Heating 2: p-TsOH / benzene / Heating 3: 1.) NBS, AIBN; 2.) silica gel, H2O / 1.) CCl4; 2.) THF, r.t. 4: 22 percent / TMSOTf, molecular sieves 4 Angstroem / CH2Cl2; diethyl ether / 7.5 h 5: 41 percent / aq. 80percent AcOH / 40 h / 45 °C 6: 82 percent / 0.1N NaOH / CH2Cl2; methanol / 0.33 h / 0 °C 7: 95 percent / 0.1N NaOH / 0.33 h / Ambient temperature View Scheme

1: 59 percent / CeCl3, n-BuLi / tetrahydrofuran; CH2Cl2 / 1 h / -78 °C 2: HgO(yellow), 20percent H2SO4 / tetrahydrofuran / Heating 3: p-TsOH / benzene / Heating 4: 1.) NBS, AIBN; 2.) silica gel, H2O / 1.) CCl4; 2.) THF, r.t. 5: 22 percent / TMSOTf, molecular sieves 4 Angstroem / CH2Cl2; diethyl ether / 7.5 h 6: 41 percent / aq. 80percent AcOH / 40 h / 45 °C 7: 82 percent / 0.1N NaOH / CH2Cl2; methanol / 0.33 h / 0 °C 8: 95 percent / 0.1N NaOH / 0.33 h / Ambient temperature View Scheme

1: p-TsOH / benzene / Heating 2: 1.) NBS, AIBN; 2.) silica gel, H2O / 1.) CCl4; 2.) THF, r.t. 3: 22 percent / TMSOTf, molecular sieves 4 Angstroem / CH2Cl2; diethyl ether / 7.5 h 4: 41 percent / aq. 80percent AcOH / 40 h / 45 °C 5: 82 percent / 0.1N NaOH / CH2Cl2; methanol / 0.33 h / 0 °C 6: 95 percent / 0.1N NaOH / 0.33 h / Ambient temperature View Scheme

1: 99 percent / HgO(yellow), 20percent H2SO4 / tetrahydrofuran / Heating 2: p-TsOH / benzene / Heating 3: 1.) NBS, AIBN; 2.) silica gel, H2O / 1.) CCl4; 2.) THF, r.t. 4: 22 percent / TMSOTf, molecular sieves 4 Angstroem / CH2Cl2; diethyl ether / 7.5 h 5: 41 percent / aq. 80percent AcOH / 40 h / 45 °C 6: 82 percent / 0.1N NaOH / CH2Cl2; methanol / 0.33 h / 0 °C 7: 95 percent / 0.1N NaOH / 0.33 h / Ambient temperature View Scheme

1: 41 percent / 80percent AcOH / 40 h / 45 °C 2: 0.1N NaOH / CH2Cl2; methanol / 0.33 h / 0 °C 3: 0.1N NaOH / CH2Cl2; methanol / 0.33 h / Ambient temperature View Scheme