1: acetonitrile / 15 h / Ambient temperature 2: CF3COOH / 0.33 h / Ambient temperature 3: acetonitrile / 15 h / Ambient temperature 4: 85.4 percent / H2, AcOH / Pd black / methanol / 3 h / Ambient temperature View Scheme

in tetrahydrofuran T=0 - 29°C; 29 h;

in acetonitrile 15 h; Ambient temperature; Yield given;

1: acetonitrile / 15 h / Ambient temperature 2: CF3COOH / 0.33 h / Ambient temperature 3: acetonitrile / 15 h / Ambient temperature 4: 1.) H2, AcOH, 2.) H+ / 1.) Pd black / 1.) RT, 5 d View Scheme