N-Cbz-2-氨基-1,3-丙二醇合成路线 (共 4 条)
反应条件
triethylamine in ethanol T=0 - 20°C;
参考文献
Jun, Young Choi; Borch, Richard F.
Organic Letters, 2007 , vol. 9, # 2 p. 215 - 218
反应条件
hydrogenchloride; triethylamine in tetrahydrofuran; 1,4-dioxane; methanol
参考文献
Bristol-Myers Squibb Company
Patent: US5962440 A1, 1999 ;
反应条件
sodium tetrahydroborate; lithium chloride in tetrahydrofuran; ethanol 18 h; Ambient temperature;
参考文献
Harada, Hiroshi; Morie, Toshiya; Hirokawa, Yoshimi; Kato, Shiro
Chemical and Pharmaceutical Bulletin, 1996 , vol. 44, # 12 p. 2205 - 2212
反应条件
1: 97 percent / 4-(dimethylamino)pyridine; imidazole / dimethylformamide / 20 °C 2: 85 percent / BiBr3 / acetonitrile / 8 h / 20 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 70, # 11 p. 4514 - 4516