2-[[环戊基]羰基]丙二酸 二乙酯合成路线 （共 5 条）
反应条件
hydrogenchloride; water T=90°C;
参考文献
F2G LIMITED
Patent: US2011/9390 A1, 2011 ;
Location in patent: Page/Page column 14-15 ;
反应条件
1: diethyl malonate With ethanol; magnesium in tetrachloromethane; toluene
1 h; Heating;
2: cyclopentane carboxylic acid chloride in tetrachloromethane; toluene
T=20°C; 1 h;
参考文献
Jung, Jae C.; Watkins, E Blake; Avery, Mitchell A.
Synthetic Communications, 2002 , vol. 32, # 24 p. 3767 - 3777
反应条件
bromine in tetrachloromethane
T=50°C; 0.75 h;
参考文献
Sakai, Takashi; Amano, Eiichiro; Kawabata, Akifumi; Takeda, Akira
Journal of Organic Chemistry, 1980 , vol. 45, # 1 p. 43 - 47
反应条件
1.1: 24 percent / NH2NH2 / ethanol / 3 h / Heating
2.1: Mg; EtOH / CCl4; toluene / 1 h / Heating
2.2: 87 percent / CCl4; toluene / 1 h / 20 °C
View Scheme
参考文献
Jung, Jae C.; Watkins, E Blake; Avery, Mitchell A.
Synthetic Communications, 2002 , vol. 32, # 24 p. 3767 - 3777
反应条件
1.1: 14 percent / 80 percent NH2NH2 / ethanol / 3 h / Heating
2.1: Mg; EtOH / CCl4; toluene / 1 h / Heating
2.2: 87 percent / CCl4; toluene / 1 h / 20 °C
View Scheme
参考文献
Jung, Jae C.; Watkins, E Blake; Avery, Mitchell A.
Synthetic Communications, 2002 , vol. 32, # 24 p. 3767 - 3777
