3-哌啶甲酸乙酯（盐酸盐）合成路线 （共 72 条）
反应条件
1: With hydrogenchloride; sodium hydroxide; diphenyl phosphoryl azide; triethylamine in ethanol; water; ethyl acetate; toluene
T=0 - 20°C;
2: With diphenyl phosphoryl azide; triethylamine in tert-butyl alcohol
T=20 - 100°C; 21.5 h;
参考文献
Eisai Co., Ltd.
Patent: EP1568699 A1, 2005 ;
Location in patent: Page/Page column 41 ;
反应条件
1: benzyl chloroformate; piperidine-3-carboxylic acid ethyl ester With triethylamine in ethyl acetate; toluene
T=0°C; 0.5 h;
2: With sodium hydroxide; water in ethanol
T=20°C;
3: tert-butyl alcohol With diphenylphosphoranyl azide; triethylamine
T=20 - 100°C; 21.5 h;
参考文献
Eisai Co., Ltd.
Patent: EP1557165 A1, 2005 ;
Location in patent: Page/Page column 87 ;
