4-甲基-4-联苯基羧酸合成路线 (共 32 条)
反应条件
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in tetrahydrofuran -78 deg C, 10 min, 20 deg C, 10 min;
参考文献
Bumagin, Nikolai A.; Luzikova, Elena V.
Journal of Organometallic Chemistry, 1997 , vol. 532, # 1-2 p. 271 - 273
反应条件
chromium(VI) oxide; acetic acid
参考文献
Journal of the Chemical Society, , vol. 32, p. 654
Chemische Berichte, , vol. 9, p. 272
参考文献
Journal of the American Chemical Society, , vol. 75, p. 2417,2420
反应条件
1: Friedel-Crafts acetylation 2: Baeyer-Villiger oxidation View Scheme
参考文献
Chemistry Letters, , p. 519 - 522
反应条件
1.1: Mg / tetrahydrofuran 1.2: 68 percent / tetrahydrofuran / 20 °C 2.1: 82 percent / KF; tri(2-furyl)phosphine / Pd(OAc)2 / dimethylformamide / 44 h / 120 °C View Scheme
参考文献
Journal of Organometallic Chemistry, , vol. 624, # 1-2 p. 208 - 216
反应条件
1: 85 percent / CuF2*2H2O / diethyl ether / 20 °C 2: 94 percent / TBAF / Pd(PPh3)4 / tetrahydrofuran / 48 h / 80 °C View Scheme
参考文献
Journal of Organometallic Chemistry, , vol. 624, # 1-2 p. 208 - 216
反应条件
sodium carbonate; palladium on activated charcoal in water Suzuki reaction; 1 h; Heating;
参考文献
Lu, Gang; Franzen, Robert; Zhang, Qian; Xu, Youjun
Tetrahedron Letters, 2005 , vol. 46, # 24 p. 4255 - 4259
反应条件
sodium hydroxide in tetrahydrofuran 2 h; Ambient temperature;
参考文献
Journal of Medicinal Chemistry, , vol. 41, # 4 p. 437 - 450
反应条件
1: 1.) n-BuLi, 2.) ZnCl2, 3.) (Ph3P)2PdCl2, (i-Bu)2AlH 2: aq. NaOH / tetrahydrofuran / 2 h / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 41, # 4 p. 437 - 450