2,3,4,5-四甲氧基苯甲酸合成路线 （共 17 条）
参考文献
Bignami; Testoni
Gazzetta Chimica Italiana, 1900 , vol. 30 I, p. 247
反应条件
urea hydrogen peroxide addition compound; sodium hydroxide in methanol; water
1.5 h; Reflux;
参考文献
Titov, Ilia Y.; Sagamanova, Irina K.; Gritsenko, Roman T.; Karmanova, Irina B.; Atamanenko, Olga P.; Semenova, Marina N.; Semenov, Victor V.
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 6 p. 1578 - 1581
反应条件
copper in methanol
18 h; Heating;
参考文献
AMAZENTIS SA; RINSCH, Christopher, L.; BLANCO-BOSE, William; SCHNEIDER, Bernard; MOUCHIROUD, Laurent; RYU, Dongryeol; ANDREUX, Penelope; AUWERX, Johan
Patent: WO2014/4902 A2, 2014 ;
Location in patent: Sheet 35 ;
反应条件
1: 96 percent / Br2 / H2O; CHCl3 / 18 h / Heating
2: 90 percent / Cu powder / methanol / 18 h / Heating
View Scheme
参考文献
Meyers,A.I.; Flisak,J.R.; Aitken,R.A.
Journal of the American Chemical Society, 1987 , vol. 109, p. 5446
反应条件
1: pyridine; ozone / methanol; chloroform / -15 °C
2: urea hydrogen peroxide addition compound; sodium hydroxide / methanol; water / 1.5 h / Reflux
View Scheme
参考文献
Titov, Ilia Y.; Sagamanova, Irina K.; Gritsenko, Roman T.; Karmanova, Irina B.; Atamanenko, Olga P.; Semenova, Marina N.; Semenov, Victor V.
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 6 p. 1578 - 1581
反应条件
1: tetrabutylammomium bromide; potassium hydroxide / 0.67 h / 100 °C / Neat (no solvent)
2: pyridine; ozone / methanol; chloroform / -15 °C
3: urea hydrogen peroxide addition compound; sodium hydroxide / methanol; water / 1.5 h / Reflux
View Scheme
参考文献
Titov, Ilia Y.; Sagamanova, Irina K.; Gritsenko, Roman T.; Karmanova, Irina B.; Atamanenko, Olga P.; Semenova, Marina N.; Semenov, Victor V.
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 6 p. 1578 - 1581
反应条件
potassium hydroxide in ethanol
4 h; Heating; Further byproducts given;
参考文献
Quijano, L.; Calderon, J. S.; Gomez, F.; Rios, T.
Phytochemistry (Elsevier), 1982 , vol. 21, # 12 p. 2965 - 2968
反应条件
potassium hydroxide in ethanol
4 h; Heating; Further byproducts given;
参考文献
Quijano, L.; Calderon, J. S.; Gomez, F.; Rios, T.
Phytochemistry (Elsevier), 1982 , vol. 21, # 12 p. 2965 - 2968
反应条件
potassium hydroxide in ethanol
72 h; Heating;
参考文献
Quijano, L.; Calderon, J. S.; Gomez, F.; Rios, T.
Phytochemistry (Elsevier), 1982 , vol. 21, # 12 p. 2965 - 2968
反应条件
methanol; diethyl ether
T=20°C; Behandeln mit Natronlauge;
参考文献
Wessely; Demmer
Chemische Berichte, 1928 , vol. 61, p. 1281
Chemische Berichte, 1929 , vol. 62, p. 123
