1-(4-羧基苯基)-3,3-二甲基三氮烯合成路线 （共 6 条）
反应条件
buffer solution pH 1.2 in ethanol T=37°C; μ=0.178; Rate constant;
参考文献
Nifontov, V. I.; Bel'skaya, N. P.; Chernov, V. A.; Ershova, Yu. A.; Validuda, G. I.; et al.
Pharmaceutical Chemistry Journal, 1984 , vol. 18, # 9 p. 592 - 596
Khimiko-Farmatsevticheskii Zhurnal, 1984 , vol. 18, # 9 p. 1037 - 1041
反应条件
buffer solution pH 1.2 in ethanol T=37°C; μ=0.178; Rate constant;
参考文献
Nifontov, V. I.; Bel'skaya, N. P.; Chernov, V. A.; Ershova, Yu. A.; Validuda, G. I.; et al.
Pharmaceutical Chemistry Journal, 1984 , vol. 18, # 9 p. 592 - 596
Khimiko-Farmatsevticheskii Zhurnal, 1984 , vol. 18, # 9 p. 1037 - 1041
反应条件
1: NO2 / 6 h / Ambient temperature
2: Ambient temperature
View Scheme
参考文献
Kaupp, Gerd; Herrmann, Andreas
Advanced Synthesis and Catalysis, 1997 , vol. 339, # 3 p. 256 - 260
反应条件
gas-solid reaction; Yield given;
参考文献
Kaupp, Gerd; Schmeyers, Jens; Haak, Michael; Marquardt, Thorsten; Herrmann, Andreas
Molecular Crystals and Liquid Crystals Science and Technology Section A: Molecular Crystals and Liquid Crystals, 1996 , vol. 276-277, p. 315 - 317
反应条件
(i) isopentyl nitrite, aq. HCl, EtOH, (ii) /BRN= 605257/, CH2Cl2; Multistep reaction;
参考文献
Gompper,R. et al.
Chemische Berichte, 1968 , vol. 101, p. 2340 - 2350
反应条件
sodium hydroxide; chloroformic acid ethyl ester; triethylamine
1.) toluene, -10 deg C, 30 min; 2.) r.t., 4 h;
参考文献
Lassiani; Nisi; Sava; Giraldi
European Journal of Medicinal Chemistry, 1983 , vol. 18, # 5 p. 401 - 403
