(S)-四氢-1,3(2H)-哒嗪二羧酸 3-叔丁酯 1-(苯甲基)酯合成路线 （共 4 条）
反应条件
1: NaHCO3 / toluene; H2O / 17 h / Ambient temperature 2: H2 / 5percent Pd-C / dimethylformamide / 18 h 3: SOCl2 / CH2Cl2 / 4 h / Ambient temperature 4: 90 percent / 1M borane in THF / tetrahydrofuran / 3 h / Ambient temperature 5: hydrazine hydrate / ethanol / 1 h / Ambient temperature View Scheme
参考文献
Attwood, Michael R.; Hassall, Cedric H.; Kroehn, Antonin; Lawton, Geoffrey; Redshaw, Sally
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1986 , p. 1011 - 1020
反应条件
1: NaHCO3 / toluene; H2O / 17 h / Ambient temperature 2: H2 / 5percent Pd-C / dimethylformamide / 18 h 3: SOCl2 / CH2Cl2 / 4 h / Ambient temperature 4: 90 percent / 1M borane in THF / tetrahydrofuran / 3 h / Ambient temperature View Scheme
参考文献
Attwood, Michael R.; Hassall, Cedric H.; Kroehn, Antonin; Lawton, Geoffrey; Redshaw, Sally
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1986 , p. 1011 - 1020
反应条件
1: aq. NaHCO3 2: 97 percent / H2 / Pd/C / methanol 3: PCl5 / tetrahydrofuran 4: N-ethylmorpholine / tetrahydrofuran View Scheme
参考文献
Attwood, Michael R.; Hassall, Cedric H.; Kroehn, Antonin; Lawton, Geoffrey; Redshaw, Sally
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1986 , p. 1011 - 1020
反应条件
1: NaHCO3 / toluene; H2O / 17 h / Ambient temperature 2: H2 / 5percent Pd-C / dimethylformamide / 18 h 3: SOCl2 / CH2Cl2 / 4 h / Ambient temperature 4: 90 percent / 1M borane in THF / tetrahydrofuran / 3 h / Ambient temperature 5: hydrazine hydrate / ethanol / 1 h / Ambient temperature 6: 10percent aq. Na2CO3 / CH2Cl2 / 5 h / Ambient temperature 7: 91 percent / HCl / CH2Cl2 / 16 h / Ambient temperature View Scheme
参考文献
Attwood, Michael R.; Hassall, Cedric H.; Kroehn, Antonin; Lawton, Geoffrey; Redshaw, Sally
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1986 , p. 1011 - 1020
