(3,4-二氢-2H-吡喃-6-基)甲醇合成路线 （共 11 条）
反应条件
1: 57.2 percent / NaH / dimethylsulfoxide / 12 h / Ambient temperature 2: 82 percent / 1.) BH3; 2.) <O>; 3: 60 percent / reagent Jones / acetone View Scheme
参考文献
Miyazaki; Ohkawa; Nakamura; Ito; Sada; Oshima; Koike
Chemical and Pharmaceutical Bulletin, 1989 , vol. 37, # 9 p. 2379 - 2390
反应条件
tert.-butyl lithium in tetrahydrofuran
T=-78°C;
参考文献
Meyers; Price, David A.; Andres
Synlett, 1997 , # SPEC. ISS. p. 533 - 534
反应条件
sodium borohydride in isopropyl alcohol
参考文献
BASF Aktiengesellschaft
Patent: US5536734 A1, 1996 ;
反应条件
lithium aluminium tetrahydride in diethyl ether
1 h;
参考文献
Bouchu, D.; Dreux, J.
Phosphorus and Sulfur and the Related Elements, 1982 , vol. 13, p. 25 - 34
反应条件
1: n-butyllithium / hexane
View Scheme
参考文献
Bouchu, D.; Dreux, J.
Phosphorus and Sulfur and the Related Elements, 1982 , vol. 13, p. 25 - 34
反应条件
2: potassium hydroxide / ethanol / 12 h / Heating
3: potassium hydroxide / benzene / 12 h / Heating
4: 74 percent / lithium aluminum hydride / diethyl ether / 1 h
View Scheme
参考文献
Bouchu, D.; Dreux, J.
Phosphorus and Sulfur and the Related Elements, 1982 , vol. 13, p. 25 - 34
反应条件
1: potassium hydroxide / benzene / 12 h / Heating
2: 74 percent / lithium aluminum hydride / diethyl ether / 1 h
View Scheme
参考文献
Bouchu, D.; Dreux, J.
Phosphorus and Sulfur and the Related Elements, 1982 , vol. 13, p. 25 - 34
反应条件
1: potassium hydroxide / ethanol / 12 h / Heating
2: potassium hydroxide / benzene / 12 h / Heating
3: 74 percent / lithium aluminum hydride / diethyl ether / 1 h
View Scheme
参考文献
Bouchu, D.; Dreux, J.
Phosphorus and Sulfur and the Related Elements, 1982 , vol. 13, p. 25 - 34
参考文献
Bouchu, D.; Dreux, J.
Phosphorus and Sulfur and the Related Elements, 1982 , vol. 13, p. 25 - 34
反应条件
sodium hydride in N,N-dimethyl-formamide
16 h; Ambient temperature;
参考文献
Miyazaki; Ohkawa; Nakamura; Ito; Sada; Oshima; Koike
Chemical and Pharmaceutical Bulletin, 1989 , vol. 37, # 9 p. 2379 - 2390
