1,4-双(3-氨基丙基)哌嗪合成路线 (共 13 条)
反应条件
hydrogenchloride
1.) ethanol, reflux 24 h, 2.) ether;
参考文献
Valenta; Nemec; Protiva
Collection of Czechoslovak Chemical Communications, 1983 , vol. 48, # 4 p. 1089 - 1096
参考文献
Carpino, Louis A.; Sadat-Aalaee, Dean; Beyermann, Michael
Journal of Organic Chemistry, 1990 , vol. 55, # 5 p. 1673 - 1675
反应条件
triethylamine in toluene
12h, 5 deg C, then 36 h, room temperature;
参考文献
Alcock, Nathaniel W.; Moore, Peter; Reader, C. James; Roe, S. Mark
Journal of the Chemical Society, Dalton Transactions: Inorganic Chemistry (1972-1999), 1988 , p. 2959 - 2964